If you like the idea of a clean inventory this idea could introduce material bags. Ranging from 4 slot bags to hold your ammo, water, food and radiation suit to 10 slot bags that will automatically fill with specific materials.
For example. A hunting bag that will fill with leather, fat, meat and eggs before filling the main inventory. Etc.
Also a larger bag that you can choose via a checkbox menu what items to auto fill it with, would be an excellent rare loot from a boss or a future high tech accessory. We could call it a smart bag.